The standard guitar tuning divides 2 ovtaves into 5 intervals of similar size, so the closest we can get to standard guitar tuning is by stacking 2\5 intervals (= 2 steps in 5ed2, or 480 cents).

53ed2 has an interval that is slightly smaller, and 72ed2 has an interval that is slightly larger. It might be interesting to stack those intervals, find suitable just intervals that approximate these ratios, and use those, or just intervals that lie between the ones generated by 21\53 and 29\72:

53ed2:

21\53 = 475.47.. ~ 21/16

42\53 = 950.94.. ~ 26/15

63\53 = 1426.41.. ~ 16/7

84\53 = 1901.88.. ~ 3/1

105\53 = 2377.35.. ~ 160/81 (< 4/1)

...

72ed2:

29\72 = 483.33.. ~ 33/25

58\72 = 966.66.. ~ 7/4

87\72 = 1450 ~ 30/13

116\72 = 1933.33.. ~ 64/21

145\72 = 2416.66.. ~ 81/40 (> 4/1)

...

For example, 53ed2 gives us (4n)ed3 (one of your examples), as well as (3n)ed(16/7). 72ed2 offers (2n)ed(7/4).

Exploring only one sequence will lead to very similar results, so in order to find actually new results it might be better to focus on intervals between (or beyond) both sequences, but not too close to the sequence generated by stacking 2\5s.